| Year | Name of Principal |
| 1845 | John Harkness, M.A., LL.D |
| 1862 | Sir Alexander Grant, M.A., Bar-At-Law |
| 1866 | Kyrle Mitford, Chatfield, B.A. |
| 1874 | William Wordsworth, B.A., LL.D., C.L.E. |
| 1890 | R.G. Oxenham, M.A. |
| 1894 | J.T. Hathornwaite, M.A. |
| 1900 | Michael Macmillan, B.A. |
| 1907 | W.H.Sharp, M.A. |
| 1909 | A.L. Converton, M.A. |
| 1926 | H.Hamill, B.A. |
| 1937 | G.V. Jathar, M.A. |
| 1942 | B.N.Seal, B.A. (Oxon.) |
| 1947 | K.R. Gunjikar, B.Sc.(Bomb.); M.A. (Cantab.) |
| 1949 | R.N.Welingkar, B.A.(Hons.), B.A. (Oxon.) |
| 1949 | S.S. Bhandarkar, B.A. (Hons.) (Bom.), B.A. (Hons.) (London) |
| 1949 | N.L.Ahmed, M.A. (Aligarh), B.Litt.(Oxon.) |
| 1957 | G.C. Bannerjee, M.A. (Bom.); B.A., B.Ltt. (Oxon.) |
| 1962 | P.S. Rege, B.A. (Hons.) (Bom.); B.Sc.(Econ.) (London) |
| 1969 | Smt. K.Wood, M.A. (Nag.); B.Litt. (Oxon.) First Lady Principal |
| 1971 | D.K.Banker, M.A. (Nag.) |
| 1976 | N.M. Dongre, M.Com. (Bom.) F.I.A. (London) |
| 1980 | Kum.H. J. Shroff, M.A. (Bom); M.A. (Oxon.); Ph.D.(Born.) |
| 1985 | N.M.Dongre, M.Com.(Com.) F.I.A. (London) |
| 1985 | M.R.Moholkar, M.A. (Poona) |
| 1986 | S.R. Mehta, M.A. (Bom.), F.I.A. (London) |
| 1988 | S.V.Gholkar, M.A. (Nagpur) |
| 1989 | Dr.P.L.Mishra, M.A. (Nag.), Ph.D. (Nagpur) |
| 1990 | Dr.S.K. Modak, M.A. (Sagar), Ph.D. (Nagpur) |
| 1991 | Dr.S.Mascarenhas, LTCL, M.A., Ph.D, D-Litt.(Bom.) |
| 1997 | Dr.N.D. Pandit, M.Sc. (Raipur), Ph.D. (Nagpur) |
| 2003 | Mrs.N.P. Charna, M.A (I/C) |
| 2004 | Dr.(Mrs.) Lakshmi Vyas M.A., Ph.D. (I/C) |
| 2005 | Asha Krishan M.A. (MUM.) M.A. (USA), Ph.D. (MUM.) (I/C) |
| 2005 | Dr.(Mrs.) Laxmi Vyas, M.A. Ph.D. (I/C) |
| 2008 | Dr.(Mrs.) Pratima Sharad Jadhav, M.Sc., B.Ed., DMLT, Ph.D. |
| 2014 | Dr.(Mrs.) Madhuri Vasant Kagalkar |
| 2020 - till date | Dr.(Mrs.) Swati Wavhal |
